Prof. Dr. Niggli Felix
Main Field(s) of Research, Abstract
The laboratory focus on cytogenetic evolution in various childhood tumors and leukemia.
& We are studying diagnostic and prognostic markers in embryonal tumors and childhood leukemia. This also includes minimal residual disease techniques in leukemia by quantitative PCR, subclass prediction in pediatric acute lymphoblastic leukemia using gene expression profiling, investigation of the relationship between genetic events in childhood embryonal tumours.
& Furthermore in collaboration with our colleagues in infectiology we establish Epstein-Barr Virus (EBV) whole genome expression profiling in EBV-associated lymphomas.
& In collaboration with colleagues in DKFZ Heidelberg we are developing a Wilms tumor mouse model.
Main Fields of Research, Keywords
Cytogenetics, embryonal tumours, acute lymphoblastic leukemia, minimal residual disease, micro array, lymphoma, EBV
Special Techniques and Equipment
A highly multidisciplinary spectrum of methods is established in the group including molecular biology, cytogenetics, FISH, FACS, real time PCR, microarray technologies
Education and Training
We have training opportunities for PhD- and MD- students and MDs interested in the research topics mentioned above.