Prof. Dr. med. Knuth Alexander

Main Field(s) of Research, Abstract
The main field of our research is the development of innovative treatment modalities for cancer patients. By eliciting cell-mediated immune responses we aim at inducing specific immunity against tumor cells. This program consists of 3 major topics, including clinical trials activities, direct assessment of tumor reactive T lymphocytes and molecular biology/SEREX-based antigen discovery. Our institute is affiliated with the Ludwig Institute for Cancer Research and the Cancer Research Institute. Both institutes have initiated an international cancer vaccine program that aims at the transition of discoveries from the laboratory in the clinic and is embedded in a collaborative academic environment. We are currently initiating clinical trials within this program. There is a close collaboration to Prof. Dr. E. Jäger at the Krankenhaus Nordwest, Frankfurt. Please contact our website to get further information on these research activities.

Main Fields of Research, Keywords
Antigen discovery, T cell immunology, clinical trial program

Special Techniques and Equipment
Serex Technology, techniques for T cell monitoring, molecular and protein biology, cell culture

Education and Training
We have training opportunities for PhD- and MD- students and postdoctoral fellows interested in our research work.